Copper Catalysed Cross-Coupling Reactions a Review

For those that are interested here is a good review:
on copper catalysed cross-coupling reactions in natural product synthesis. written by Professor Evano from the Universit ́e Libre de Bruxelles. It appeared in Nat. Prod. Rep., 2013, 30, 1467

From the abstract” Copper-catalyzed Ullmann–Goldberg-type cross-coupling reactions have undergone nothing short of a renaissance over the last decade and an impressive number of procedures are now available for the formation of C–N, C–O and C–S bonds with remarkable efficiencies and surgical precision. These reactions have been recently integrated into natural product synthesis, which clearly resulted in the emergence of new retrosynthetic paradigms and bond disconnections. The impact of copper-catalyzed cross-coupling reactions in natural product synthesis will be overviewed in this article with an emphasis on the evolution of strategies due to copper catalysis, mostly by comparison with alternative tactics and their relative efficiencies.

If you have journal access through your library of place of work have a look.

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Prof. dangerdackel (199 Posts)

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